TB-500 10mg

Description

Advanced Cellular Migration & Soft Tissue Regeneration Peptide

TB-500 is a synthetic fraction of a naturally occurring protein called Thymosin Beta-4, which is found in high concentrations in human and animal blood platelets. Composed of 7 amino acids, this short peptide chain represents the exact active region responsible for the parent protein’s legendary cellular repair, tissue recovery, and anti-inflammatory properties.

For researchers investigating muscle repair, tendon flexibility, endothelial cell movement, and advanced wound healing, TB-500 is a cornerstone compound for soft tissue regeneration studies.

Technical Specifications

• Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala (Active 7-amino acid fragment)
• Molecular Formula: C38​H59​N9​O16​S
• Molecular Weight: 929.98 g/mol
• Purity: ≥99% (HPLC verified)
• Appearance: Clean, white lyophilized powder
• Format: Lyophilized sterile powder

Core Research Mechanisms

Unlike structural proteins that stay fixed in place, TB-500 operates as a systemic signaling agent, traveling through cellular matrixes to actively drive the mechanics of physical repair:

• Actin Binding & Cell Migration: TB-500 directly regulates actin, a crucial protein responsible for a cell’s internal structural scaffolding. By binding to actin, the peptide acts as a catalyst for cellular migration, allowing healing cells to travel quickly to the exact site of an injury.
• Angiogenesis (New Capillary Growth): The compound stimulates the growth of new blood vessels from existing ones. This process quickly restores blood flow, oxygen, and nutrient delivery to slow-healing, low-vascularity tissues like ligaments, tendons, and cartilage.
• Dermal and Structural Collagen Deposition: TB-500 influences the behavior of keratinocytes and fibroblasts, ramping up the deposition of collagen to swiftly repair skin lesions, muscle tears, and structural tissue defects.
• Down-Regulation of Inflammatory Cytokines: It works on a cellular level to suppress toxic inflammatory markers, which drastically reduces local swelling and keeps scar tissue buildup to an absolute minimum.

Documented Research Applications

• Musculoskeletal and Tear Recovery: Extensively utilized in pre-clinical animal models to study the accelerated repair of strained muscles, torn ligaments, and joint capsule damage.
• Cardiovascular and Ischemic Research: Looked at closely in cardiac models to evaluate how thymosin fractions help protect and remodel heart tissue following oxidative stress or restricted blood flow.
• Systemic Healing Capacity: Because of its low molecular weight, TB-500 travels easily through tissues, allowing researchers to study systemic, full-body healing responses rather than just localized effects.

Storage & Handling

• Long-Term Storage: Store the lyophilized powder frozen at -20°C or colder to maintain maximum peptide stability. Keep protected from moisture and direct light.
• Reconstitution: Gently mix with Bacteriostatic Water. Because TB-500 is a delicate peptide chain, do not shake or agitate the vial aggressively after adding liquid—gently swirl until the powder disk is completely dissolved.
• Post-Reconstitution Storage: Once mixed, store the solution in a refrigerator between 2°C and 8°C. For maximum testing accuracy and consistency, use the reconstituted solution within 30 to 45 days.

FOR LABORATORY RESEARCH USE ONLY: This compound is strictly intended for in vitro and in vivo laboratory research and cellular evaluation. It is not approved for human consumption, therapeutic use, or clinical prescription.